UNIVERSITY OF MADRAS
B.Sc. DEGREE COURSE IN BIO-CHEMISTRY
SEMESTER SYSTEM WITH CREDITS
(Effective from the Academic Year 2003-2004)
SYLLABUS

Application Oriented Subject-II - Immunology

Duration: 3 hrs
Maximum Marks: 100
Credits: 4

(90 hrs)

1. Immunity and its types. Innate immunity, determinants of innate immunity. Acquired immunity, active and passive immunity. Commonly used toxoid vaccines, killed vaccines, live attenuated vaccines, bacterial polysaccharide vaccines. (18 hrs)

2. Immunity

Humoral and cellular immunity, immunoglobins-structure and function, types of antibodies. (18 hrs)

3. Antigens-nature, immunogens, haptens. Cells involved in antibody formation, differentiation of lymphocyte, clonal selection theory, cooperation of T-cell with B-cell, secretion of antibody, genetic basis of antibody diversity. (18 hrs)

4. Antigen Antibody Interactions

Antigen-antibody reactions in vivo and iv vitro. Complement fixation reaction, monoclonal antibody-preparation and application in biology. (18 hrs)

5. Immunological disorder:

Immunological tolerances and immuno suppression, hypersensitivity and allergy, histocompatibility antigens-elementary knowledge, autoimmune disease, transplantation immunology. (18 hrs)

Text books recommended

1. Essential Immunology - Roitt
2. Immunology - Weir
3. Text book if Microbiology - Ananthanarayanan and Panicker