UNIVERSITY OF MADRAS
B.Sc. DEGREE COURSE IN CHEMISTRY
SEMESTER SYSTEM WITH CREDITS
(Effective from the Academic Year 2003-2004)

Application Oriented Subject - Applied Chemistry-I

Duration: 3 hrs
Maximum Marks: 100
Credits: 4

(Common To All)

Preparation, Synthesis and Structure determination are not required for the compounds mentions.

Unit - I

Pharmaceutical Chemistry I

1. Definition of the following terms - drug, pharmachophore, pharmacology, pharmacopeia, bacteria, virus and vaccine.

2. Causes, symptoms and drugs for anaemia, jaundice, cholera, malaria and filaria.

3. Indian medicinal plants and uses - tulasi, neem, kixhanelli, mango, semparuthi, dadodai and thoothuvalai.

4. Antibacterials Suipha drugs - examples and actions - prontosil. suiphathiazole, suiphafurazole - Antibiotics - definition and action of penicillin, streptomycin, chloramphemcol. eythromycein - tetracyclines. SAR of chioramphenicol only.

5. Antiseptics and disinfectants - definition and distinction - phenolic compounds, chioro compounds, cationic surfacts.

Unit - II (20 hrs) Pharmaceutical Chemistry II

1. Analgesics - Definition and actions - narcotic and non narcotic - morphine and its derivatives, pethidine and methodone - disadvantages and uses, Antipyretic analgesics - salicylic derivatives, paracetamol, ibuprofen.

2. Drugs affecting CNS - Definition, distinction and examples for - tranqualisers, sedatives, hypnotics, psychedelic drugs - LSD, hashish - their effects.

3. Anaesthetics - Definition - local and general - volatilenitrous oxide, ether, chloroform, cyclo propane - uses and disadvantages - non volatile - intravenous - thiopental sodium, methohexitone, propanidid.

4. Causes, medicines amid their mode of action for the treatment of - cancer, antineoplatics - diabetes - hypoglycemic agents. AIDS - AZT, DDC.

5. Blood - Grouping, composition, Rh factor, blood pressure, hypertension and hypotension.

Unit - III (20 hrs) Biological Chemistry and Dairy Chemistry

1. Elementary treatment of digestion and absorption of carbohydrates, proteins and fats.

2. Elementary treatment of enzymes, coenzymes, cofactors, prosthetic groups and theory of enzyme action.

3. Physiological functions of adrenaline, thyroxin, oxytocin, insulin and sex harmones.

4. Micronutrients and their biological role in human systems.