University of Madras - Syllabus of Bachelor of Science (BSc) Microbiology - Semester III - Paper III - MCC-301 - Immunology
UNIVERSITY OF MADRAS
B.Sc. DEGREE COURSE IN MICROBIOLOGY
SEMESTER SYSTEM WITH CREDITS
(Effective from the Academic Year 2003-2004)
SYLLABUS
Semester III - Paper III - MCC-301 - Immunology
Duration of Examination: 3 hrs
Max Marks: 100
Credits: 4
Unit I :
History of Immunology, Immunohaematology, structures composition and functions of cells and organs involved in immune system. Blood groups. Blood transfusion - Rh incompatibilities. Host-parasitic relationships. Microbial infections, virulence and host resistance. Innate immunity, Acquired immunity.
Unit II :
Antigens, types, properties, Haptens, adjuvants; Vaccines - Types - Toxoids - antitoxins. Immunoglobulins. Structure, types and properties. Theories of antibody production. Complement structure properties, function of complement components and pathways. Antigen antibody reaction; Invitro methods: precipitation reactions, agglutination, complement fixation, Inmiunofluroscence ELISA, RIA. Invivo methods: skin tests - immune complex tissue demonstations.
Unit III:
Hypersensitivity Reactions - Antibody mediated - Typed I anaphylaxis - Type II Antibody dependent cell cytotoxicity - Type III - Immune complex reaction - the respective reaction. Cell mediated immune response - Lymphokines, cytokines.