UNIVERSITY OF MADRAS
B.Sc. DEGREE COURSE IN Zoology
SEMESTER SYSTEM WITH CREDITS
(Effective from the Academic Year 2003-2004)

SYLLABUS

Semester V - Paper V - Cell Biology

Duration of Examination: 3 hrs
Maximum Marks: 100
Credits: 4

Unit I

History of Cell Biology - Tools and Techniques of Cell Biology Cell Fractionraction, Homogenization Centrifugation, Isolation of sub cellular Components. Biochemical Techniques - Chromatography - Electrophoresis and their Application, Tissue Culture and Cell Culture Techniques. Histological Techniques - Staining - Vital Stains - Cytoplasmic and Nuclear Stains Micro Technique - Methods, Microscopes - Types - Light, Phase contrast, SEM, TEM - Units of measurement.

Unit II

Cell - Cell theory - Viruses -Types and Structure - Bacteria - Bacterial membrane - Ultra structure of Plant & Animal cell - Cytoplasm - Structure and Composition, Function - Extra Cytoplasmic Structure - Cilia Flagella - Cytoplasmic Inclusions.

Unit III

Cell components - Plasma Membrane Ultra Structure - Different Models - Functions - Ultrastructure, Composition and Function of Endoplasmic reticulam, Ribosomes, Golgi Complex, Lysosomes, Centrioles, Plastids, Chloroplasts, Microtubules & Microfilaments, Mitochondria, and Microsomes.

Unit IV

Nucleus - Ultrastructure, Composition and Functions - Nuclear Membrane - Nucleoplasm - Chromosomes - Heterochromatin and Euchromatin - Nucleolus - Nucleolus Cycle - DNA and RNAs - Protein Synthesis & regulation.

Unit V

Cell Divisions and Cell Cycle - Amitosis, Mitosis and Meiosis and their Significance - Cancer, Ageing of Cells and Stem cell studies.

REFERENCE:

1. Ambrose, E.J. and Dorothy, M. Easty, 1970. Cell Biology, Thomas Nelson & Sons Ltd., 500 pp.

2. Burke, Jack. D., 1970. Cell Biology, Scientific Book Agency, Calcutta.

3. Cohn, N. S., 1979, Elements of Cytology, Freeman Book Co., New Delhi - 110 007, 495 pp

4. DeRobertis, E.D.P. and E.M.F. DeRobertis, 1988. Cell and Molecular Biology, 8^th Edition, International Edition, Infomed, HonKong, 734pp.

5. Giese, A.C., 1979. Cell Physiology, Saunders Co., Philadelphia, London, Toronto, 609 pp.

6. Power, C.B., 1989. Essential of Cytology, Himalaya Publishing House, Bombay - 400 004, 368 pp.

7. Dowben, R., 1971. Cell Biology, Harper International Edition. Harper and Row Publisher, New York, 565 pp.

8. VeerBala Rastogi, Introductory cytology. Kedar Nath Ram Nath. Meerut 250 001.

9. Verma, P.S. and V. K.Agarwal, 1995. Cell and Molecular Biology, 8^th Edition, S.Chand & co., New Delhi - 110 055, 567 pp.

10. Loewy, A.G. and P.Sickevitz, 1969. Cell Structure and Function, Amerind Publishing Co., NewDeihi - 110 020, 516 pp.

11. Swansen, C.P. and P.L.Webster, 1989. The Cell, Prentice Hall of India Pvt. Ltd., New Delhi - 110 001, 373 pp.

12. Simplified course - Cell Biology - S.Chand & Company - 2000