UNIVERSITY OF MADRAS
B.Sc. DEGREE COURSE IN BIO-CHEMISTRY
SEMESTER SYSTEM WITH CREDITS
(Effective from the Academic Year 2003-2004)
SYLLABUS

Semester II - Paper II - Bio organic Chemistry II

Duration: 3 hrs
Maximum Marks: 100
Credits: 4

Unit I

Definition and classification of lipids. Fatty acids - classification, nomenclature, structure and properties. Classification, structure and function of prostaglandins, triacyiglycerols. Chemical properties of fats - iodine value, Sap value, acid number, Rancidity, Rm value (18 hrs)

Unit II

Chemical properties and functions of phospholipids and their structures. Lecithins, cephalins, phosphatidyl serine, phosphatidyl inositol, plasmalogens, glycolipids( cerebrosides and gangliosides), isoprenoids and sterols ( chiosterol and zymosterol), steroids (steroid hormones, bile acids and bile salts). Biological significance of fats. (18 hrs)

Unit III

Nature of genetic material. Isolation of RNA and DNA. Composition of RNA and DNA. Structure of purine and pyrimidines, nucleosides and nucleotides (18 hrs)

Unit IV

Size and structure of different types of DNA-A, B, Z types of DNA. Structure and role of different types of RNA. Properties of nucleic acids - denaturing and annealing of DNA (18 hrs)

Unit V

Hetero cyclic rings of biologically important compounds. Structure and biological importance of pyridine, pyrole, quinolene, pyrimidine, purine, pteridine, thiazole, imidazole and indole ring containing compounds. Porphyrine - structure and biologically important compounds containing porphyin ring, bile pigments - structure and biological importance (18 hrs)

Books