University of Madras - Syllabus of Bachelor of Science (BSc) Bio-Chemistry - Semester VI - Paper XI - Clinical Biochemistry-I
UNIVERSITY OF MADRAS
B.Sc. DEGREE COURSE IN BIO-CHEMISTRY
SEMESTER SYSTEM WITH CREDITS
(Effective from the Academic Year 2003-2004)
SYLLABUS
Semester VI - Paper XI - Clinical Biochemistry-I
Duration: 3 hrs
Maximum Marks: 100
Credits: 4
(60 hrs)
1. Basic concepts of clinical Biochemistry
A brief review of units and abbreviations used in expressing concentrations and standard
solutions. Specimen collection and processing (blood ,urine and feaces), anti-coagulant
and preservatives for blood and urine. Transport of specimens.
(12 hrs)
2. Hematology
Total and differential counting of leukocytes. RBC counting. Prothrombin time and hematocrit Types of anaemias, hemophilias.
(12 hrs)
3. Diseases related to carbohydrate metabolism
Blood glucose regulation, hypo and hyperglycemia. Diabetes mellitus-types, clinical features, metabolic changes. Glycosuria, galactosemia and fructosuria. Glycogen storage disease.
(12 hrs)
4. Diseases related to aminoacids and nucleic acid metabolism Etiology and clinical manifestation of phenyl ketonuria, cystinuria, alkaptonuria, Fanconi's syndrome, albinism and tyrosinemia, hypo and hyperuricemia, Gout.
(12 hrs)
5. Diseses related to lipid metabolism:
Serum lipids in diseases with special reference to cholesterol, lipidosis, triglyceridemia. hypo and hypercholesterolemia. Clinical features of atherosclerosis and fatty liver.
(12 hrs)
Books recommended:
1. Text book of clinical Biochemistry-Cart. A.Burdis and Edward R.Ashwood.
2. Text book of medical biochemistry-M.N. Chatterjee ariçl Rane shinde.
3. Clinical Biochemistry-Hoffmann.
4. Biochemistry with clinical correlation.- Devlin.
5. Practical Clinical Biochemistry- Harold Varley.